NeuroHope Therapeutics, Inc. - Publications

J. Gao, M. Khang, Z. Liao, Ken Webb, Megan Detloff, and Jeoung Soo Lee. “Rolipram-loaded PgP nanoparticle reduces secondary injury and enhances motor function recovery in a rat moderate contusion SCI model”, (2023) Nanomedicine: Nanotechnology, Biology, and Medicine. 53: 102702. DOI: 10.1016/j.nano.2023.102702.

Christian Macks, Daun Jeong, Michael Lynn, and Jeoung Soo Lee. “Therapeutic efficacy of rolipram delivered by PgP nanocarrier on secondary injury and motor function in a rat TBI model.” (2022) Nanomedicine. 17(7):431-445.PMCID: PMC8905552 ;DOI: 10.2217/nnm-2021-0271.

Morgan Chandler, Lewis Rolband, M. Brittany Johnson, Da Shi, Yelixza I. Avila, Edward Cedrone, Damian Beasock, Leyla Danai, Elizabeth Stassenko, Joanna K. Krueger, Jiancheng Jiang, Jeoung Soo Lee, Marina A. Dobrovolskaia, Kirill A. Afonin. “Expanding structural space for immunomodulatory nucleic acid nanoparticles (NANPs) via spatial arrangement of their therapeutic moieties”, Advanced Functional Materials (2022) Oct, 32 (43).

Joshua Woo and Jeoung Soo Lee. “Effect of lyoprotectants on long-term stability and transfection efficacy of lyophilized poly(lactide-co-glycolide)-graft-polyethylenimine/plasmid DNA polyplexes.” (2021) Nanomedicine. 16(15):1269-1280. PMCID: PMC8293032 ;DOI: 10.2217/nnm-2021-0065.

Christian Macks, Daun Jeong, Michael Lynn, and Jeoung Soo Lee. “Local delivery of RhoA siRNA by PgP nanocarrier reduces inflammatory response and improves neuronal cell survival in a rat TBI model.” Nanomedicine: Nanotechnology, Biology, and Medicine (2021) 32:102343. PMCID: PMC8714129 ;DOI: 10.1016/j.nano.2020.102343.

Justin Halman, Ki-Taek Kim, So-Jung Gawk, Richard Pace, Morgan B Johnson, Morgan R Chandler, Lauren Rackley, Mathias Viard, Ian Marriott, Jeoung Soo Lee (Co-corresponding author), and Kirill Afonin, “A cationic amphiphilic co-polymer as a carrier of nucleic acid nanoparticles (NANPs) for controlled gene silencing, immunostimulation, and biodistribution”. Nanomedicine, Nanotechnology, Biology, and Medicine, (2020) 23 102094. PMCID: PMC6942546 ; DOI: 10.1016/j.nano.2019.102094.

Jayesh Betala, Sooneon Bae, Eugene M. Langan 3^rd, Martine LaBerge, and Jeoung Soo Lee. “Combinatorial therapy of sirolimus and heparin by nanocarrier inhibits restenosis after balloon angioplasty ex vivo.” Nanomedicine. (2020) 15(12):1205-1220. PMCID: PMC7466912 ;DOI: 10.2217/nnm-2020-0028.

So-Jung Gwak and Jeoung Soo Lee. “Suicide Gene Therapy By Amphiphilic Copolymer Nanocarrier for Spinal Cord Tumor”, Nanomaterials (2019) 9(4):573. PMCID: PMC6523721 ; DOI: 10.3390/nano9040573.

Sooneon Bae, Michael J. DiBalsi, Nicole Meilinger, Chengqi Zhang, Erica Beal, Guzeliya Korneva, Konstantin G. Kornev, Jeoung Soo Lee. “Heparin-Eluting Electrospun Nanofiber Yarns for Antithrombotic Vascular Sutures” ACS Applied Materials and Interfaces (2018) 10(10):8426-8435. DOI: 10.1021/acsami.7b14888.

Christian Macks, So Jung Gwak, Michael Lynn, Jeoung Soo Lee. Rolipram-Loaded Polymeric Micelle Nanoparticle Reduces Secondary Injury after Rat Compression Spinal Cord Injury, Journal of Neurotrauma (2018) 35(3):582-92. PMCID: PMC5793955 ; DOI: 10.1089/neu.2017.5092.

So-Jung Gwak, Christian Macks, Sooneon Bae, Noah Cecil, and Jeoung Soo Lee. Physicochemical stability and transfection efficiency of cationic amphiphilic copolymer/pDNA polyplexes for spinal cord injury repair, Scientific Report (2017) 7(1):11247. PMCID: PMC5595900 ; DOI: 10.1038/s41598-017-10982-y.

So-Jung Gwak, Christian Macks, Mark Kindy, Michael Lynn, Ken Webb, and Jeoung Soo Lee, RhoA knockdown by PgP/RhoA siRNA polyplex enhances axona regeneration after spinal cord injury, Biomaterials (2017) 121:155-166. PMCID: PMC5315572 ; DOI: 10.1016/j.biomaterials.2017.01.003.

So-Jung Gwak, Justin Nice, Jeremy Zhang, Benjamin Green, Christian Macks, Sooneon Bae, and Ken Webb, and Jeoung Soo Lee. Cationic, amphiphilic polymeric micelle as a nucleic acid carrier in the rat spinal cord. Acta Biomaterialia (2016) 35:98-108. PMCID: PMC4829463 ; DOI: 10.1016/j.actbio.2016.02.013.